Domperidone: UK Status and Risks
Domperidone is not a UK-licensed product for sale in the UK. It can still show up in some listings, but no MHRA review of its safety or effectiveness covers it.
Consult a qualified clinician before acting on it, and treat bold marketing claims about it with caution. A missing or unclear UK licensing status is worth a direct question to the seller.
Not UK-licensed. This medicine is not supplied through UK-registered pharmacies.
Sellers list the active ingredient as domperidone. The MHRA has not assessed what these products actually contain.
The MHRA warns that medicines sold outside registered pharmacies can be counterfeit, contaminated, or contain the wrong amount of active ingredient. Buy prescription-only medicines from a pharmacy registered in the UK.
Pharmacies by area for Domperidone (UK-licensed equivalent)
- North East · 884 pharmacies
- North West · 2538 pharmacies
- Yorkshire and The Humber · 1676 pharmacies
- East Midlands · 1307 pharmacies
- West Midlands · 1778 pharmacies
- East of England · 1860 pharmacies
- London · 3261 pharmacies
- South East · 2368 pharmacies
- South West · 1374 pharmacies
- Northern Ireland · 714 pharmacies
- Scotland · 1725 pharmacies
- Wales · 1050 pharmacies
Pharmacies near you
Use your location to open the pharmacies closest to you and ask them about Domperidone, the UK-licensed medicine with the same active ingredient.
Cities with the most pharmacies
- London · 724 pharmacies
- Birmingham · 265 pharmacies
- Nottingham · 180 pharmacies
- Glasgow · 177 pharmacies
- Leeds · 173 pharmacies
- Sheffield · 162 pharmacies
- Bristol · 148 pharmacies
- City of London · 144 pharmacies
- Manchester · 134 pharmacies
- Edinburgh · 131 pharmacies
- Bolton · 124 pharmacies
- Belfast · 122 pharmacies
- Hampstead · 121 pharmacies
- Coventry · 115 pharmacies
- Cardiff · 112 pharmacies
About Domperidone
Domperidone is not a licensed medicine in the United Kingdom and cannot legally be sold there as a medicine. It is also advertised under the name Motilium.
The product's marketing material does not list forms or strengths, leaving uncertainty about its contents. A doctor or pharmacist can discuss the advertised product, potential risks and appropriate treatment options.
Claimed strengths are manufacturer claims, but no strength or dosage form is listed for this product. There is therefore no stated strength to report or assess. The product name should not be used to infer its contents, and this page does not establish a dosing schedule or an appropriate amount for treatment.
What Domperidone is used for
The marketing material does not specify what this Domperidone product is claimed to treat, so a particular marketed use cannot be confirmed. Domperidone belongs to a class of medicines associated with reducing nausea and vomiting and affecting movement in the upper digestive tract.
That general pharmacological context does not establish that this advertised product is suitable or effective for those symptoms. An advertised name alone cannot establish the contents, quality or likely benefit of a product.
How Domperidone works
Domperidone is a dopamine receptor antagonist. Dopamine is a chemical messenger involved in several bodily functions, including signalling associated with nausea and movement through the digestive tract. Blocking certain dopamine receptors can reduce signals involved in vomiting and encourage movement in the upper digestive tract.
These are general effects of the active ingredient, not verification of this product's contents or performance. The same pharmacological activity can also affect hormone levels, and domperidone has clinically significant risks involving the heart's electrical rhythm.
Main interactions
- Other medicines that prolong the heart's electrical recovery time can increase the risk of dangerous rhythms.
- Strong inhibitors of the enzyme CYP3A can increase domperidone exposure, including certain antifungal medicines and antibiotics.
- Medicines that lower potassium or magnesium can increase heart rhythm risks.
- Anticholinergic medicines may oppose effects on digestive tract movement.
Key warnings
- This product lacks licensing as a medicine in the United Kingdom; its contents and quality have not been independently verified.
- Domperidone can cause serious disturbances of the heart's electrical rhythm.
- Heart rhythm disorders, significant electrolyte disturbances and liver disease can increase safety concerns.
- Palpitations, fainting or collapse during use require urgent medical assessment.
- Dopamine receptor blockade can raise prolactin levels and cause breast-related or menstrual effects.
Pregnancy and breastfeeding
The marketing material does not specify pregnancy or breastfeeding data. Domperidone can pass into breast milk, and its effects on prolactin do not establish that use during breastfeeding is appropriate. Any proposed use during pregnancy or breastfeeding should be discussed with a doctor or pharmacist, considering both maternal safety and possible effects on the baby.
Missed dose
A missed-dose plan cannot be established for this product because its dosage form and strength are not listed. Doubling a dose to compensate can increase adverse effects, including heart rhythm risks. A doctor or pharmacist can clarify an appropriate plan after checking the actual product and any other medicines involved.
Storage
No storage conditions or dosage form are listed for this product. General medicine storage practice is to retain the original packaging, protect it from excess heat and moisture, and keep it out of the sight and reach of children.
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First published October 2, 2026 · Last updated · Report an error on this page